manip

diamond cleaver

For easily handling and mounting of section ribbons. The mounting of the manipulator is easy. The original plate on the cryochamber is removed, the manipulator is fixed in 5 minutes.

Applications

  • Frozen hydrated biological samples (CEMOVIS)
  • Room temperature sectioning of water sensitive samples
    • Dry resin sectioning of biological samples for chemical analysis
    • Dry sectioning of industrial samples such as polymers

Functionality

  • The left manipulator moves a conductive fibre on which the sections are attached by electrostatic force; the growing ribbon is guided.
  • The right manipulator guides the grid very precisely below the section ribbon, the sections are attached to the carbon film with electrostatic force.

Compatibility

  • Leica cryochambers FC6 and FC7 equipped with a Crion ionizer/charger
  • Adaption on other cryochambers upon request

References

The cryosectioning approach is described by Struder et al.:

Struder, D., Klein A., Iacovache, I, Gnaegi, H., and Zuber B. (2014). A new tool based on two micromanipulators facilitates the handling of ultrathin cryosection ribbons. Journal of Structural Biology, 185, 125-128.

Ordering Information

Diamond Knives can be ordered online using a credit card or purchase order number for payment. Click to order an Manip.

Diamond Knives can be ordered by phone at 215-412-8390 or fax 215-412-8450.

 

Your benefits of working with Diatome

Free customer service

Sectioning tests with biological and material research specimens of all kinds.

We send you the sections along with the surfaced sample, a report on the results obtained and a recommendation of a suitable knife.

Complete discretion when working with proprietary samples.

Re-sharpening and reworking service

A re-sharpened Diatome diamond knife demonstrates the same high quality as a new knife.

Even knives purchased in previous years can continue to be re-sharpened.

All knives can be reworked into another type of knife for no extra charge, e.g. ultra to cryo or 45° to 35°.

Exchange service

Whenever you exchange a knife we offer you a new Diatome.

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Contact Us

1560 Industry Road
P.O. Box 410
Hatfield, PA 19440
tel: 215.412.8390
fax: 215.412.8450
email: sgkcck@aol.com

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